Overview

Ensure faster analysis with expanded compound coverage in the latest release of this essential MS spectral library

One of the most trusted mass spectral libraries has once more been extensively updated. The NIST / EPA / NIH EI Mass Spectral Library 2026, developed by the experienced mass spectrometry team at the National Institute of Standards and Technology (NIST), represents the culmination of more than four decades of comprehensive evaluation and expansion, making it an essential resource for confident compound identification across GC-MS workflows.

The 2026 edition contains over 431,000 critically evaluated electron ionization spectra for over 376,000 unique compounds to deliver reliable identifications across environmental, forensic, pharmaceuticals, food and industrial applications.

What's included

• Electron Ionization (EI) mass spectral library (in native manufacturer formats)
• GC Retention Index (RI) library
• NIST 2026 Software: MS Search, AMDIS, MS Interpreter
  • Now includes GC-MS chromatogram analysis!

Available from Wiley in the most common instrumentation manufacturer formats, NIST 2026 is a necessity for any laboratory engaged in GC-MS analysis.

Ask about our Wiley Registry / NIST and KnowItAll packages

Bundle additional data to ensure the most comprehensive coverage and powerful tools to optimize and automate your workflow. 

Library Specifications

Electron Ionization (EI) Library

• Spectra: 431,000+
• Unique Compounds: 376,000+
• Chemical Structures: 431,000+
• AI-RI Values for all EI compounds

EI Library is available in native instrument manufacturer formats.

GC Retention Index (RI) Library

• RI Values: 527,900+
• Unique Compounds: 216,000+

188,198 compounds from the GC-RI library are also in the EI library

Compound Coverage

This database covers a broad range of compounds including:

• Metabolites
• Food & fragrances
• Drugs/Pharmaceuticals
• Forensics
• Pesticides/Pollutants
• Industrial surfactants
• Petrochemicals
• Glycans-Lipids-Sugars

What’s New in this Release?

In the latest release:

• The NIST/EPA/NIH EI Mass Spectral Library has added over 35,000+ new compounds, now containing 431,000+ EI spectra, with an emphasis on compounds that are biologically, environmentally, or industrially relevant.
• The GC Retention Index Library added over 35,000 compounds.
• The NIST MS Search software has been extensively updated and now also includes full GC-MS chromatogram analysis!

Compatibility

• Compatible with most current and legacy mass spectrometry data systems.
• Also available in bundles with KnowItAll software, which supports multiple instrument vendor formats.

For full compatibility information please visit sciencesolutions.wiley.com/compatibility.

Ordering Information