KnowItAll Solutions for MS
Powerful Software. Quality Data.
Results You Can Rely On.
KnowItAll offers solutions to identify, analyze, and manage your MS data. Combined with the world’s largest spectral reference databases, it provides one of the most advanced technologies available for fast, reliable spectral analysis.
With the NEW KnowItAll 2023, Wiley continues to expand KnowItAll’s MS capabilities, with tools to automate mass spectrometry processing and accelerate analysis workflows.
| Key Features |
|---|
| Automated Non-Targeted GC-MS Analysis |
| Spectral Search |
| Processing |
| Database Building / Management (Supports Multiple Techniques / Instruments) |
| Integrated Toolsets for Structure Drawing, Reporting, & More |
| Comprehensive High-Quality Libraries of MS Reference Spectra* |
Available in English, Japanese, Chinese, French, and German.
Now with accessibility features such as keyboard access to menus, audio narration for icons, tool tips.
*Subscription required to KnowItAll Spectral Libraries.
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Automated Non-Targeted GC-MS Analysis
NEW! MS Expert – Combines Deconvolution with Spectral Search into an Automated Workflow
GC-MS data analysis can be time consuming, especially when examining complex analytes. The new MS Expert automatically processes, deconvolutes, and analyzes GC-MS data.
Combined with KnowItAll’s fast database search, it accurately suggests matches to knowns and allows unknowns to be further examined.
How Does It Work?
Simply import a GC-MS data file and the software automatically deconvolutes the TIC into components. All extracted component MS spectra are then automatically searched against reference libraries* to find matches. Results are shown as a hit list for each component.
Unidentified components or components with low match scores can then be sent to KnowItAll’s SearchIt tool for manual investigation. In SearchIt, one can use adaptive search to match similar components or use mixture analysis to separate coeluted components.
Spectral Search
Sophisticated MS Search for Confident Identification & Classification
Wiley offers sophisticated tools to search and compare unknown mass spectra with KnowItAll’s high-quality reference spectra* or user generated databases.
With fast search speeds, powerful algorithms, and advanced technologies, Wiley aims to deliver results you can rely on.
Tools That Set KnowItAll Apart
NEW! Wiley’s Patent-Pending Adaptive Search for MS: This technology finds spectral matches that are similar to the unknown but have additional or missing selective fragment(s). It then suggests what might be causing the differences, where possible. This feature provides tremendous insight into structural possibilities to explore when there is no exact match. Ultimately, this may lead to more intelligent and confident identification and confirmation.
Mixture Analysis of MS Spectra: One of the most powerful features is KnowItAll’s ability to analyze mixtures. When searching an unknown against a reference database, you can choose to search for multiple components. The result is a series of composite spectra, each accompanied by the individual component spectra that comprise the composite spectrum, as well as the residual spectrum (difference between the query and the composite spectrum). Composite spectra are then ranked by how closely they resemble the query spectrum.
Processing
GC-MS Data Processing
With ProcessIt, users can view and select a mass spectrum or the average of mass spectra and define the background. The selected mass spectrum or extracted spectra can be transferred for database searching or imported into a user database.
Spectral Data Management
Build Single or Multi-Technique Databases from Various Vendors
Because Wiley Science Solution’s primary business is spectral databases, KnowItAll is built through years of experience in doing just that—building databases.
Researchers can build searchable databases that include one or more analytical techniques (IR, MS, Near IR, NMR, Raman, UV-Vis), chemical structures, and other meta data. So even if a laboratory’s instruments come from multiple manufacturers, KnowItAll can archive the data.
Integrated Tools for Structure Drawing, Reporting, & More
ChemWindow 2D Structure Drawing Program & Communications Tools
Because structures are critical to your work, we included all the tools you need to streamline your workflow and save time.
ChemWindow is the software chemists worldwide choose for chemical structure drawing. It provides an advanced set of drawing tools that’s easy to use— just click and drag to draw any chemical structure. Access the most comprehensive set of tools to draw rings, bonds, atoms, electrons, charges, chains, arrows, and more.
And with KnowItAll’s ReportIt tool, create standard reports, papers, and presentations that include annotations, tables of data, spectra, 2D and 3D structures, and more.
And Many More Value-Added MS Tools!
Mass Fragmentation Tool
Isotopic Distribution Tool
Elemental Composition Calculator
KnowItAll Spectral Libraries
The Most Comprehensive Data for Results You Can Rely On
Spectral Analysis software is not complete without a high-quality database of reference spectra. And with KnowItAll, Wiley offers the best of both!
The KnowItAll Wiley Mass Spectral Library* is a trusted data source that provides over 914,000 mass spectra of the highest quality.
Increase access to over 1.2 million spectra by adding NIST and other data options.
Compatibility
For file formats supported, visit sciencesolutions.wiley.com/compatibility
KnowItAll and ChemWindow are trademarks of John Wiley & Sons, Inc. in certain jurisdictions.
*Subscription required to KnowItAll Spectral Libraries.