Platform-Independent Search Algorithm for Mass Spectrometry
Reliable LC-MS/MS libraries and search algorithms had been considered impossible until Wiley, working with the Oberacher Group, created MSforID—a complete search and library building software development kit (SDK) for LC-MS/MS. MSforID has been proven accurate in clinical settings:
- >95% Specificity
- <0.7% False negative
- 97.5% True positive
- Testing an alternative search algorithm for compound identification with the ‘Wiley Registry of Tandem Mass Spectral Data, MSforID'
- On the inter-instrument and interlaboratory transferability of a tandem mass spectral reference library: 1. Results of an Austrian multicenter study
- On the inter-instrument and interlaboratory transferability of a tandem mass spectral reference library: 2. Optimization and characterization of the search algorithm