What's New in KnowItAll 2026
KnowItAll is better than ever with new tools and advances for spectral analysis.
Wiley’s KnowItAll software offers solutions to identify, analyze, and manage analytical and chemical data. Combined with Wiley’s comprehensive, high-quality spectral reference libraries, it provides an unparalleled solution for fast, reliable spectral analysis.
KnowItAll 2026, the latest version of Wiley’s comprehensive software suite for spectral analysis and analytical data management, introduces the new Trendfinder that integrates chemometric analysis directly into the familiar KnowItAll interface.
Below is a summary of the many exciting updates. Access to features and data depends on the user’s license and edition of the software you are using.
NEW! Trendfinder: Discover hidden pattens and trends in datasets.
Trendfinder applies Principal Component Analysis (PCA) to help you uncover patterns in complex datasets—whether you’re working with spectra or chromatograms. It’s designed to make trend detection and relationship mapping intuitive, even if you don’t have a background in chemometrics. You can use your own data or tap into KnowItAll’s collections* to explore correlations, outliers, and hidden structures that might otherwise go unnoticed.
Additional highlights in this release
- Expanded language support: KnowItAll is now available in Korean (한국어)
- Security strengthened: Comprehensive security audit completed, reinforcing KnowItAll’s commitment to protecting sensitive analytical data
- Microsoft Installer (MSI) deployment: KnowItAll can now be deployed centrally by IT organizations silently onto desktops for enterprise/campus deployments
- New file filters:
- Shimadzu (LCMS, .lcd)
- Nanalysis (NMR, .jdx)
- New for LC-MS:
- New peak m/z search algorithm featuring exact mass only improves matching capabilities for computed spectral libraries
- Manual processing mode added in LC Expert for greater analytical control
- More database searching controls in LC Expert
- Batch processing of raw LC-MS chromatograms in LC Expert to streamline component identifications even further
- New for NMR:
- Automatic multiplet assignment for H-NMR
- Automatic multiplet assignment for H-NMR
- New for GC-MS:
- Renamed “MS Expert” to “GC Expert” to better distinguish workflows
- Selected databases from GC Expert can be sent to SearchIt, along with a selected component MS for further exploration
- Single or multiple peak label viewing is now possible
- Smoother transfer of selected extract/raw spectra to SearchIt
- Retention Index search now possible
- ID Expert application:
- Now allows users to select databases to search
- MS metadata can be reviewed
- MineIt application:
- Allows renaming of a property
- Created “Computed RI” field for AI Retention Indices
- Database record “history” tracking provides audit trails of user database modifications
- Allows user to zoom on a structure
- SearchIt application:
- Users can now paste a list as a field query so users can search multiple criteria simultaneously for more efficient data exploration
- GC/LC-MS now allows a partial spectrum search
- Add Retention Index (RI) search to GC-MS spectrum search
- Transfer Software Developers’ Kit (SDK):
- Can now handle GC-MS run in a folder
- Can pre-select LC-MS search user interface: MSforID or Spectrum Search
- InChI is upgraded to version 1.07
- Bug fix:
- Updated Shimadzu .lcd file filter
- Improved fourier transform for NMR; improvement for .jdx and .jdf
- Training Documents Updated: Our extensive KnowItAll tutorial documents have been updated and new chapters have been added. This series of lessons provides tutorials the user can follow along with here.
Compatibility
KnowItAll and ChemWindow are trademarks of John Wiley & Sons, Inc. in certain jurisdictions.
*Subscription required to spectral libraries and various features/options.