Chemical profiling of the RK44 extract using high-resolution electrospray ionization mass spectrometry (HR-ESIMS) and Global Natural Product Social (GNPS) molecular network (MN) showed a cluster of low molecular weight metabolites with a characteristic 250 nm UV absorption, suggesting that they share a common chromophore skeleton. Database dereplication using AntiBase 2017 (WILEY) and other online databases revealed that these metabolites have not been previously described in the literature.
View ResourceSignalling and Bioactive Metabolites from Streptomyces sp. RK44
Technique: LC-MS
Type: Case Studies: Scientific Literature
Applications: Metabolomics, Pharmaceutical & Biotech
Products: AntiBase Library - Wiley Identifier of Natural Products